Abstract
BACKGROUND: Electrocardiography (ECG) is simple, quick and economic investigation for
diagnosis of acute coronary syndrome. Its applicability in prediction of left main coronary
artery/ 3 vessel coronary disease can be of very useful in saving precious time in the critical
care of coronary patients.
OBJECTIVE: Electrocardiography changes as a predictor of left main coronary artery / 3 vessel
coronary disease in patients presenting with Non-ST segment elevation acute coronary
syndrome.
METHODOLOGY: This cross sectional study was executed from July 2014 to June 2015 at Isra
University hospital Hyderabad taking 114 consecutive patients of age >20, of either gender,
presenting with symptoms of Non-ST segment elevation MI or that showed ECG changes in lead
aVR. Informed written consent for the study was taken from the immediate family members of
patients. Approval from ethics review committee of Isra University was taken. Data analysis was
done through SPSS. Descriptive statistics (Mean ±standard deviation for continuous & frequencies and percentages for categorical variables) were expressed.
RESULTS: Patients’ mean ±SD age was 56.65 ±15.44 years (Range: 20-89 years). Male to female
ratio was 3.4:1. More than a half (52%) of these patients had Left main (LM) / 3 vessels disease.
About a quarter other (25%) had 2 vessels while (22%) had single vessel disease (P value
<0.0001). Patients having ST elevation in lead aVR, were associated with increased risk of
developing LM / three vessels disease (P value <0.0001).
CONCLUSION: ST elevation in lead aVR and ST depression in leads II, III, and aVF can be
practically used for evaluation left main / 3 vessel disease among NSTE-ACS patients.
Nandlal Rathi, Muhammad Zaman Baloch, Raj Kumar Sachdewani, Feroz Memon. (2016) Frequency of Left Main Artery/Three Vessel Disease Predicted through ECG Changes in Patients Presenting with Non-ST Segment Acute Coronary Syndrome, Journal of Liaquat University of Medical and Health Sciences, Volume-15, Issue-2.
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