Abstract
Purpose: To evaluate the efficacy of a single intravitreal Bevacizumab injection either immediately after cataract surgery or during cataract surgery for the management of postoperative decrease of vision in patients with DME.
Material and Methods: Randomized, controlled, open-label, parallel group study of 60 eyes of 60 patients, having diabetic macular edema and lens opacity (of more than grade 3). The primary end-point was change in BCVA at 6 weeks compared with that at baseline using the Snellens acuity testing charts.
Results: The mean changes in BCVA at 6 weeks compared with that at baseline were a worsening of visual acuity in the control group (no injection) and an improvement of visual acuity in the Bevacizumab group (p = 0.01).
Conclusions: Intravitreal Bevacizumab after cataract surgery appears to be beneficial in preventing post- surgical visual loss in eyes with diabetic retinopathy by reducing the chance of macular thickening.
Mazhar ul Hassan, P.S Mahar, Aziz ur, Rehman, Nasir Bhattt, Asfandyar, Asgahr, Ashraf Daud. (2010) Randomised Controlled Trial to evaluate the effects of Intravitreal Bevacizumab administration on Visual Outcome in Diabetic Patients with Diabetic Macular Edema who Underwent Cataract Surgery, Pakistan Journal of Ophthalmology, Volume 26, Issue 3.
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