Male adult albino Wistar rats (n=30), aged 10-12 weeks and weighing 180-200g of weight were divided in two equal
groups. Group-A (control), received no intervention and Group-B received single dose of 20mg/kg of methotrexate (MTX)
intraperitoneally. Liver was harvested and its architecture was assessed microscopically. Mean hepatocyte count, hepatocyte diameter
and hepatocyte nuclear diameter were calculated with micrometer