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Objective: The purpose of this was study to analyze the advantages/disadvantages of venting versus non-venting incision in descemet stripping automated endothelial keratoplasty (DSAEK). Material and Methods: This study was performed in the department of Ophthalmology, Khyber Teaching Hospital Peshawar, Pakistan from 1st Jan 2017 to April 2019. The charts of all patients were reviewed retrospectively. DSAEK was performed by a single surgeon, using a similar technique. Any complication either intra- or post-operative which happened, was recorded and managed either medically or by appropriate surgical means. At the end of the study the data was compiled and analyzed. Results: Total 21 patients, 5 (23.80%) males and 16 (76.20%) females were included in this study. The mean age of the patients was 52.62±7.64 years. All patients had pseudophakic corneal edema/bullous keratopathy. Twenty (95.23%) out the total had posterior chamber intraocular lens and only 1 (4.7%) had anterior chamber intraocular lens. All patients had visual acuity of less than 5/60 (0.08). Mean value before DSAEK procedure was 0.0381 ± 0.01721. Best corrected visual acuity (BCVA) after DSAEK in venting cases was 6/24 (0.25) in one case (4.76%), 6/36 (0.16) in one case (4.76%), 6/60 (0.1) in four cases (19.04%) and 3/60 (0.05) in four cases (19.04%). Mean values after DSAEK in venting cases was 0.2810±0.19393 (p-value 0.004). BCVA after DSAEK in non-venting was 6/12 (0.5) in one case (4.76%), 6/18 (0.32) in one case (4.76%), 6/24 (0.25) in four cases (19.04%), 6/36 (0.16) in one case (4.76%) and 6/60 (0.1) in four cases (19.04%). Mean value after DSAEK in non-venting cases were 0.2164±0.12372 (p-value 0.001). P-values after DSAEK in venting versus non-venting cases were 0.001. Donor dislocation was seen in 4.76%, air induced pupillary glaucoma in 9.52% and partial donor non-attachment in 4.76% in the venting cases. Air induced pupillary glaucoma 4.76% and partial donor non-attachment in 4.76% are the only early post operative complication in non-venting cases. Conclusion: DSAEK is a promising procedure for decompensated cornea which has damaged endothelium. The complications are more in venting than the non venting cases and similarly best corrected visual acuity remain good in non-venting cases.

Zaman Shah, Bakht Samar, Ibrar Hussain. (2020) DESCEMET STRIPPING AUTOMATED ENDOTHELIAL KERATOPLASTY (DSAEK), VENTING VERSUS NON-VENTING INCISION - A REVIEW OF 21 CASES, Journal of Medical Sciences, Volume 28, Issue 3.
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