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The case of a 69-year-old man with bilateral synchronous
tonsillar carcinoma is reported. The patient complained of
nasal closure, strange voice, and discomfort in his pharynx
when he was admitted to the Department of
Otolaryngology Head and Neck Surgery at Wakayama
Medical University, Wakayama, Japan, in March 2017. The
palatine tonsils were enlarged and the surface was
irregular. Left cervical lymphadenopathy was also
evident. Histological examination from both tonsils was
performed and bilateral tonsillar squamous cell
carcinoma was diagnosed. PCR analysis showed the same
HPV-DNA pattern from bilateral tonsils.
Concurrent chemoradiotherapy was performed. Total 70
Gy of irradiation (2Gy/day×35 day) was applied to
bilateral tonsillar tumours and upper neck. Follow up was
conducted every three months and the patient was free
of recurrence for three years. Patient's informed consent
was taken to publish the case report.
Shunji Tamagawa, Mehmet Gunduz, Muneki Hotomi, Keisuke Enomoto , Esra Gunduz, Kenji Warigaya. (2021) A case report of synchronous bilateral tonsillar carcinoma associated with human papilloma virus , Journal of the Pakistan Medical Association, Volume 71, Issue 1.
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