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Objective: To determine the preventive effect of turmeric on mosquito coil smoke induced emphysema in rat
lungs.
Study Design: Randomized control trial.
Place and Duration of Study: The study was completed in six months duration in the department of Anatomy,
Islamic International Medical College, Rawalpindi, in collaboration with National Institute of Health (NIH),
Islamabad.
Materials & Methods: Twenty one adult male albino rats were divided into 3 equal groups. Control group X was
kept in fresh air. Experimental Group M was exposed to Mosquito Coil smoke for eight weeks. Group T received
oral turmeric 300mg/kg body weight and had a coil smoke exposure as well. All rats were dissected after 8
weeks and lung tissue was examined microscopically. The statistical significance of the results was calculated by
applying Pearson chi square test and the obtained results were compared statistically.
Results: Marked emphysema was observed in the histological sections of rat lungs from experimental group M
showing alveolar septal destruction and bullae formation in the lung tissues of all animals (100%) in group M.
Emphysema was present in 1 out of 7 rats in group T thus group T showed a significant protection with only 15%
of animals with emphysematous lungs.
Conclusions: Mosquito coil causes emphysema in the lung tissue and turmeric proves to be protective against
this damage.
Saira Jawed, Rehana Rana, Shazia Muazzum, Sabiha Muhummad Haq. (2018) Effect of Turmeric on Mosquito Coil Induced Emphysema in Rat Lungs, Journal of Islamic International Medical College, Volume-13, Issue-3.
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