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The coronavirus disease 2019 (COVID-19) has claimed around 1 million lives across the globe and infected over 30 million word population since its origination from Wuhan china in December 2019. The clinical symptoms, presentation, and mortality rate of COVID-19 are highly variable among different world populations. The Chinese population of Wuhan city has a 3% mortality rate, from the beginning of this epidemic to till date, but the mortality rate increased twofold in Italy, Spain, and the USA after China1,2. The European countries and the USA emerged as the new epicentre of COVID-19 after china. The severity of the disease in Italian patients and rapid deterioration of patient health, resulting in increased mortality rate indicate the involvement of other factors, which alleviate the viral pathogenicity. The severity of the disease and response of the patients to available management strategies have shown significant diversity and success rates among people of different ethnic backgrounds. Pakistan is the country in south Asia, where 1st COViD -19 patient was reported in February 2020. The progression of the infection, clinical severity, and the mortality rates are low in the Pakistani region as compared to its ethnically matched neighbour country India and the developed countries of European and American regions. World health organisation has listed Pakistan among the countries where the report of new cases of COVID-19 and the death toll is going towards lower side with every passing day. In addition, the successful efforts of the government of Pakistan, for controlling the spread of the infection and managing hospitalized patients have been commended by world health leaders. Apart from the successful administrative strategies for combating the disease; several other factors,
Ikram Din Ujjan. (2020) Covid-19: Factors for Global Variations in Disease Severity and Mortality, Journal of Liaquat University of Medical and Health Sciences, Volume-19, Issue-3.
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