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Small intestine polyps are very rare in adults. Incidental finding of those polyps; sending them for
histopathology that comes out to be Peutz-Jeghers syndrome (PJS) is extremely rare. PJS is an
inherited disease characterized with typical hamartomas polyps in intestine along with distinctive skin
pattern and mucocutaneous pigmentation. Gene mutation is responsible for 93% of PJS cases, among
which majority of cases occur due to mutation in STKII gene.
PJS patients have 15-fold higher risk of developing cancer, including intestinal, extra-intestinal, breast,
lung, pancreatic and colorectal cancer. Although PJS incidence is very low but its early recognition is
very important for lowering morbidity and mortality. In this study, we have reported a very rare case of
PJS in adults that was operated for small bowel obstruction secondary to intussusception. These cases
are very rare in literature.
Shahid Nazir, Ambreen Munir, Sehrish Sulman, Qazi Waleed-u-Zaman, Aisha Yar Muhammad. (2020) Jejunal Polyps that Lead to Small Bowel Intussusception in Adults: A Rare Case Report, Journal of Liaquat University of Medical and Health Sciences, Volume-19, Issue-2.
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