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OBJECTIVE: To determine the factors causing peritonitis and deaths at Jinnah Hospital Karachi.
METHODOLOGY: The study included 216 patients with acute peritonitis who underwent exploratory
laparotomy from 2016 to 2018. Surgical treatment according to cause and post-operative treatment of
disease carried out. Histopathological report and other diagnostic test like typhoid dot test and blood
culture results were recorded and resultwas analyzed by SPSS version 24.
RESULTS: Frequent causes of acute peritonitis were typhoid intestinal perforation 62(28.70%),Peptic
ulcer perforation 54 (25%), rupture appendix 38 (17.59%), tuberculous intestine perforation 26 (12.05%),
gangrene gut 14 (6.48%), large gut tumor perforation 10 (4.62%), ruptured liver abscess 4 (1.85%),
ruptured gall balder 4 (1.85%) and acute pancreatitis 4 (1.85%). Complications were septic shock 30
(13.88%), paralytic ileus 16 (7.40%), burst abdomen 12 (5.5%) and mortality was 8 (3.70%.)
CONCLUSION: Infectious diseases like typhoid, H-pylori PUD, ruptured appendix, ruptured liver
abscess, and TB intestine are common causes of peritonitis.
Mariam Malik, Mazhar Iqbal, Abdul Malik Magsi, Sughra Parveen, Muhammad Iqbal Khan, Munazza Shamim, Shoaib Malik. (2019) Causes of Acute Peritonitis and its Outcome in Tertiary Medical Centre, Journal of Liaquat University of Medical and Health Sciences, Volume-18, Issue-3.
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