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OBJECTIVE: To determine the benefits of elective splenectomy in selected patients with thalassemia major. STUDY DESIGN: Prospective descriptive study. PLACE OF STUDY: Liaquat University Hospital Jamshoro. DURATION OF STUDY: July 2014 to June 2015. PATIENTS AND METHODS: 27 selected patients of Thalassemia major were evaluated after open elective splenectomy via midline incision for the benefits achieved post operatively. RESULTS: Out of 27 patients 19 (70.3%) were male and 08(29.6%) were female, age ranges from 5-10 years with a mean age of 7 years. Out of 27 patients, 25 patients (81.48%) had a uneventful recovery, only 2 patients (7.4%) developed post-operative complications. No mortality was observed in this series. Post-operative long term maintenance of adequate hemoglobin and improved quality of life was observed in 26(96.29%) patients. Only 1(3.7%) patient who developed postoperative incisional hernia was not satisfied with the procedure. CONCLUSION: We conclude that splenectomy is a safe and beneficial procedure in selected patients of thalassemia major.

Abdul Salam Memon, Riaz Memon, Agha Taj Muhammad, Syed Asad Ali, Akmal Jamal Siddiqui. (2017) Splenectomy: Does it help in Patients with Thalassemia Major, Journal of Liaquat University of Medical and Health Sciences, Volume-16, Issue-1.
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