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OBJECTIVE: To determine frequency of metabolic syndrome in patients with Schizophrenia, in
a tertiary care armed forces setup.
STUDY DESIGN: Cross sectional study.
PLACE AND DURATION: Department of Psychiatry, PNS SHIFA, Karachi from October 2009 to
April 2010.
MATERIALS AND METHODS: Fifty six patients with Schizophrenia reporting for management in
PNS SHIFA were enrolled as subjects. Demographic variables and other confounding variables
were recorded in a structured Performa, Blood Pressure (BP) and Waist Circumference (WC)
were measured while Fasting Plasma Glucose (FPG), Triglycerides (TAG) and HDL-Cholesterol
(HDL-C) levels were estimated by routine methods in laboratory with quality assurance.
RESULTS: More than half i.e.30 (53.6%) of subjects had Metabolic Syndrome (MS) as per ATP IIIA criteria. Further 25% (n=14) of subjects were positive for two components of MS. Low HDL-C
levels were most prevalent component followed by hyperglycaemia, hypertriglyceridemia and
increased WC while hypertension was least common component.
CONCLUSION: Metabolic Syndrome and its various components are frequently co morbidity in
patients with Schizophrenia.
Ata Ullah, Shahab Muhammad Khan, Farrukh Hayat Khan, Sheraz Afzal Malik, Aamir Ijaz. (2015) Metabolic Syndrome in Patients with Schizophrenia, Journal of Liaquat University of Medical and Health Sciences, Volume-14, Issue-2.
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