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Objective: To compare peak expiratory flow rates amongst smokers and nonsmokers. Methods: This cross sectional study was carried out at 1 Mountain Medical Battalion and PAF Hospital Rafiqui from January to March 2014. Healthy male adults accompanying patients were selected by non-probability convenience sampling after verbal consent. Exclusion criteria included females, asthmatics, respiratory tract infections or patients unable to comprehend the technique of using peak flow meter. Hand held Mini-Wright peak flow meter was used to measure peak expiratory flow rate (PEFR) in a standing position. Best of three attempts was recorded. Height, weight and chest circumference were measured. History of smoking was obtained and quantified in terms of pack years. Results: 376 individuals were stratified into three groups: group 1 (18-26 years) having 116 individuals including 29 (25.00%) smokers; group 2 (27-34 years), having 147 individuals including 56 (38.10%) smokers; and, group 3 (35 years or older) with 113 individuals including 44 (38.94%) smokers. Smokers in group 1 had a 4.19% lower PEFR than nonsmokers (P=0.077). Smokers in group 2 and 3 had PEFRs 7.83% and 15.50% lower than those of nonsmokers respectively (P<0.001). Smokers had much lesser PEFR than predicted values as compared to nonsmokers (P<0.05 for all age groups). Smoking load increased with age. There was a significant negative correlation between the number of pack years and PEFR (R= -0.359; p<0.001). Conclusion: Smokers have lower peak expiratory flow rates as compared to nonsmokers, the difference being directly related to the amount of smoking.

Abdul Rehman Arshad, Ghulam Abbas Khan Niazi, Ammad Akram Chaudhary. (2014) Smoking related airflow limitation in asymptomatic healthy adults, , Volume-39, Issue-4.
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