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Mefenamic Acid is anti-inflammatory drug used to treat pain. The focus of this research work was the validation of mefenamic acid tablets to ensure their quality and efficacy by applying various physical and chemical parameters such as weight variation, % age assay, friability, disintegration time (DT), hardness and loss on drying (LOD) by comparing with standards parameters of British Pharmacopoeia (BP) and United States Pharmacopoeia (USP). The validation was conducted during the preparation process as it was easy to remove any shortcomings during the process rather than after the completion of the manufacturing process. Further, the validation is also necessary to achieve batch-to-batch consistency during the product manufacturing. This method is precise, accurate and very simple to analyse mefenamic acid tablet. This qualitative data can help for further improvement of the mefenamic acid drug efficiency.
MUHAMMAD ASLAM, AYESHA IDRESS, MISBAH IRSHAD, ASAD GULZAR, SYED SALMAN SHAFQAT, AMINA ASGHAR, ZAHRA NOREEN, MUHAMMAD KHALID, RASHID MEHMOOD, UMAIR AHMAD. (2021) Process validation of mefenamic acid tablets by spectroscopic method, Biologia – Journal of Biological Society of Pakistan, Volume 67(I), Issue 1.
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