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In the arena of latest technologies, researchers are looking for a unique treatment strategy for diagnosis and treatment of cancer; it is a second chief cause of deaths in the world. Advances in chemotherapeutic agents, various radiological techniques and bio-nanoparticles treatments (i.e., green synthesized metallic nanoparticles) attracted many researchers to conclude a novel cancer treatment strategy. Unluckily every strategy had some working limitations as a result of which cancer remained a catastrophe for humanity. The present review article devised the modern cancer treatment paradigm which proposed directions towards probiotics or biotics-cancer treatment strategy. The probiotics are present in the human gut region and acting as a health promoter; as they have antioxidative, immunomodulatory, antipathogenic and anti-cancerous properties. Review based on the futuristic and modern aspects of cancer treatment, we believe that probiotics based cancer treatment would be supportive to overcome the chemotherapeutic and radiological drawback sand provides an appropriate cancer treatment strategy. Anticipating various challenges, we expect that probiotics may become a potential cancer bio-theranostic in the field of medical sciences shortly. Appropriate monitoring and treatment are strongly recommended to prevent hepatocellular carcinoma complications.

Shaukat Ali, Sadia Batool, Fatima Javed Butt, Sundas Nasreen, Hafiz Muhammad Tahir. (2019) Hepatocellular Carcinomas Risk Factors, Diagnosis, Prevention and Frontier to Probiotic Treatment, Punjab University Journal of Zoology, Volume 34, Issue 2.
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