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The aim of the present study was to identify bioactive constituents of the ethyl acetate fraction of methanolic root extract of quinoa (Chenopodium quinoa Willd.) through GC-MS analysis. For this purpose, crushed roots of the plant were extracted with methanol for two weeks. The extract was concentrated by evaporating the solvent on a rotary evaporator followed by addition of distilled water and subsequent fractionation using n-hexane, chloroform and ethyl acetate. The ethyl acetate fraction was subjected to GC-MS analysis and nine compounds were identified, including undecane (1), benzene, nitro- (2), -ascorbic acid 2,6-dihexadecanoate (3), octadec-9-enoic acid (4), benzene,1,1’- (oxydi-2,1-ethanediyl) bis 3-ethyl- (5), cis-9-hexadecenal (6), 1,2-benzedicarboxylic acid, diisooctyl ester (7), 10- nonadecanone (8) and 1-triacontanol (9). Literature survey revealed that most of the identified compounds possess diverse biological activities. Compounds 1, 6 and 7 are reported to possess antimicrobial activity. Compounds 3 and 6 are antioxidants. Compounds 3, 4, 7, 8 and 9 possess diverse medicinal properties including anti-inflammatory, antiinfertility, cancer and cardio protective, anti-mutagenic, and/or wound healing, antifouling. The present study concludes that ethyl acetate fraction of root extract is a good store house of bioactive constituents.
Iqra Haider Khan, Arshad Javaid, Dildar Ahmed, Uzman Khan. (2020) IDENTIFICATION OF VOLATILE CONSTITUENTS OF ETHYL ACETATE FRACTION OF CHENOPODIUM QUINOA ROOTS EXTRACT BY GC-MS, , Volume 17, Issue 1.
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