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Objective of study was to evaluate the serum level of Ischemia Modified Albumin (IMA) and total oxidative stress as a biomarker for diagnosis of ischemic heart disease prone to myocardial infarction. The present study was conducted in the Department of Biochemistry, University of Karachi with assistance of Liaquat National Hospital and National Institute of Cardiovascular Diseases, Karachi-Pakistan. Subjects were grouped according to selection criteria, three case group and control group. Total of 250 subjects, 100 in control group and 150 in case group (50 subjects in each group A, B and C) was included. Mean age (years) in control group was 47.41 ± 5.91, in group-A was 49.1 ± 5.8, in group-B was 49.0 ± 5.69 and in group-C was 51.1 ± 6.68. High mean ± SD values of IMA (µm/L) were observed for group C (97.58 ± 14.13) followed by group B (89.12 ± 5.48) and group A (84.68 ± 16.38) as compare to control group (22.49 ± 11.05). Statistically significant results were observed for IMA, troponin-I, SOD and TAC between group A, B, C and control group.
Jai Parkash Panjwani, Faizan-ul-Hassan Naqvi, Ruqaya, Iftikhar Ahmed Siddiqui, Farhan Essa, Asher Fawwad, Umaira Zakir. (2019) ROLE OF ISCHEMIA MODIFIED ALBUMIN AND TOTAL OXIDATIVE STRESS AS A BIOMARKER IN THE DIAGNOSIS OF MYOCARDIAL INFARCTION IN PAKISTANI POPULATION, , Volume 16, Issue 3.
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