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Cocos nucifera L. (family Arecaceae) is known to be helpful in treating physiological disorders. Thin layer chromatography, qualitative phytochemical test and disc diffusion method were used to evaluate the antimicrobial activity of Cocos nucifera (L.) extract against Shigella dysenteriae, Bacillus subtilis, Escherichia coli, Shigella sonnei, Pseudomonas aeruginosa and Staphylococcus aureus. TLC analysis of coarse coconut shell extract showed that fine extract of shell sample found to be more effective for extraction of phytochemicals. Coconut shell is rich in phytochemical (alkaloid, reducing sugar, saponins, tannins, flavonoid, terpenoids, resins and sterol) while phenols quinones and proteins are absent in coconut shell. Reducing sugar, tannins, flavonoid, terpenoid, resins, sterols, phenol and quinones are major phytochemical constituent of coconut leaves while alkaloid, protein, and saponins were absent. Coconut shell extracts showed significant activity against P. aeruginosa, B. subtilis, E. coli, S. sonnei, and S. dysenteriae.

Syeda Hira Bukhari, Suraiya Jabeen, Nimra Ayub, Umme Laila Awan, Sundus Fatima, Shagufta Ishteyaque. (2019) SCREENING OF COCOS NUCIFERA L. AS A SOLUTION TO ANTIMICROBIAL RESISTANCE, , Volume 16, Issue 3.
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