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The aim of present study was to screen various phytochemicals, antioxidant and antidiabetic investigation of ethanolic extract of whole plant of Psammogeton biternatum Edgew. which belongs to family Apiaceae. Phytochemical analysis showed the presence of phenols, flavonoids, alkaloid, terpenoids and tannins. Saponins were absent. The antioxidant activity was evaluated using different tests viz., Total phenolic content, total flavonoids content, FRAP, DPPH and βcarotene linoleic acid assay. It was observed that Total phenolic content showed maximum value i.e., 2.83±0.008 GAE mg/mL while Total flavonoid content was 2.50±0.01, and FRAP value were i.e., 1.92 ± 0.00 respectively. Antidiabetic potential of ethanolic extract of P. biternatum Edgew. (300mg/kg) were studied for 15 days in which following parameters were investigated i.e., Blood glucose, body weight, food consumption, water intake and organs weight. The STZ induced diabetic rats exhibited a heavy loss in weight and increase in blood glucose level. While oral intake of P. biternatum Edgew. (300mg/kg) extract showed maximum reduction in plasma glucose level from day 1 to 15 i.e., 314.67±0.88, 172.67±0.88 and 126.83±0.87 respectively. In diabetic rats administration of 300mg/kg extract have better sugar lowering effect than Metmorphine. Its antioxidant properties may reduce oxidative stress and hence prevent the diabetes. The present findings support the usage of P. biternatum for the treatment of diabetes after clinical trials.
Muhammad Ajaib, Muhammad Changaiz, Aziz-ul-Hassan, Muhammad Asif Iqbal, Khizar Hayat Bhatti. (2019) EVALUATION OF THE ANTIOXIDANT AND ANTIDIABETIC PROPERTIES OF PSAMMOGETON BITERNA, , Volume 16, Issue1.
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