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Fasciola gigantica is a common liver parasite in ruminants in Pakistan including goat. This infection is of great economic and public health importance. But the studies on tissue damage caused by this infection are meager specieally in goat. Therefore, observations are made by the study of histological sections of infected liver of goat Microscopic observations revealed severe host tissue reaction and damage including bile duct hyperplasia and fatty degeneration of liver. There was a quantitative increase in the number of cells of bile duct epithelium increasing the volume of the duct. Fatty degeneration indicates severe injury and was obvious by the accumulation of fat vacuoles within parenchymal cells resulting into a foamy appearance under the microscope. Dilated sinusoids, fibrosis, and vascular changes were also observed.
F. M. Bilqees, Imrana Shabbir. (2006) BILE DUCT HYPERPLASIA AND FATTY DEGENERATION IN GOAT LIVER INFECTED WITH FASCIOLA GIGANTICA, , Volume 3, Issue 3.
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