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The workup of corona virus disease (COVID-19) involves analyzing samples for acute or past presence of SARS-CoV-2 (virus). A detection of 2019 novel Corona virus (2019-nCov) by real-time reverse transcriptase polymerase chain reaction (RT-PCR) indicates current infection and positive IgG antibody level implies a prior infection. Imaging techniques like high resolution computed tomography (HRCT) chest and Xray chest helps in diagnosing and monitoring the disease. Most cases of 2019-nCov are mild and range from asymptomatic carriers to critical illness leading to acute respiratory distress, septic shock and multiorgan failure. We report two cases of COVID-19 who manifested with high grade fever, myalgias, cough and shortness of breath on minimal exertion. All baseline laboratory findings were normal. Initial RT-PCR was negative for oropharyngeal and nasopharyngeal swabs. CT Chest showing typical peripheral patchy and ground glass opacities bilaterally, other markers of infectivity followed by antibody titer confirms the disease.
Dr Shoaib Asghar, Junaid Mustafa, Arsalan Ahmad Khan Durrani, Habib Ur Rehman, Sohaib Asghar, Muhammad Usama. (2022) ROLE OF CT CHEST AS FIRST CHOICE FOR EARLY DIAGNOSIS OF COVID-19 PNEUMONIA EVEN IN RT-PCR NEGATIVE CASE, JOURNAL OF AYUB MEDICAL COLLEGE ABBOTTABAD, Volume 34, issue 2.
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