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Background: This study was conducted to determine the outcome of trans-rectal ultrasound(TRUS) guided biopsy of prostate for the detection of prostatic carcinoma in a single tertiary care hospital in Pakistan.Methods: This is a retrospective study including three hundred and eighty-three patients who underwent trans rectal ultrasound guided biopsy of prostate in a single tertiary care hospital. Indications for biopsy were raised prostate specific antigen(PSA), abnormal digital rectal examination(DRE) and/or both. Twelve core biopsy of prostate was done.Results: The overall detection rate of prostate cancer was 59%. Prostate cancer detection in various PSA ranges of 0–3.99, 4–9.99, 10–19.99 and >20 ng/ml are 22.22%, 37.88%, 50.0% and 89.9%. PSA density >0.15ng/ml2 can diagnose 74.5% of patients with cancer.Prostate cancer detection rate based on abnormal DRE is 64.6% compared to 60.8% detected by PSA>4 ng/ml.Conclusion:In conclusion raised PSA, smaller prostate volume, abnormal DRE and raised PSA density are associated with greater chances of detection of prostate carcinoma.
Dr. Muhammad Waqas,, Durre Shohab,, Mohammad Athar Khawaja, Afifa Masood, , Muhammad Waqas Iqbal, , Saeed Akhter. (2018) OUTCOME OF TRANS RECTAL ULTRASOUND GUIDED TWELVE CORE BIOPSY OF PROSTATE FOR THE DETECTION OF PROSTATECANCER- A SINGLE CENTRE EXPERIENCE, JOURNAL OF AYUB MEDICAL COLLEGE ABBOTTABAD, Volume 30, Issue 1.
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