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We report a case of a 38-year-oldU.A.E national who presented with malignant hypertension and features of thrombotic microangiopathy. He presented witholiguria, renal failure, thrombocytopenia and haemolyticanaemia. He required several sessions of renal replacement therapy. ADAM 13 mutational analysis was sent to differentiate Thrombotic micro angiopathy due to thrombotic thrombocytopenic purpura (TTP) or malignant hypertension. Renal biopsy revealed histopathological features of malignant arteriolar nephrosclerosis (MANS). Haemolytic parameters improved after control of blood pressure andhe was subsequently discharged with early nephrology follow up.
Dr Ishma Aijazi, , Fadhil Al Shama,, Lakshmiah Ganapathy Raman,, Sara Mukhtiar. (2017) MALIGNANT HYPERTENSION COMPLICATED BY RENAL THROMBOTIC MICRO ANGIOPATHY: ROLE OF ADAM 13 MUTATIONAL ANALYSES, JOURNAL OF AYUB MEDICAL COLLEGE ABBOTTABAD, Volume 29, Issue 3.
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