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To determine the frequency of Chikungunya virus (CHIKV) infection in the tertiary care hospital of ststKarachi during the time from 1January 2017 till 31December 2018.Study Design: This was aretrospective cross-sectional study.Place and Duration of Study: The study was conducted in the Department of Microbiology, Dow Diagnostic ststReference and Research Laboratory, Karachi, Pakistan from 1January 2017 till 31December 2018. Materials and Methods: Serum of suspected patients of Chikungunya virus infection was separated from venous blood samples and checked for immunoglobulin M (IgM) antibodies against Chikungunya virus infections by applying a micro titer plate assayELISA). Data was collected after enzyme-linked immunosorbent (the approval of ethical committee of Dow University of Health Sciences by Pacslink software and analysis was accomplished by using Statistical Package for Social Science SPSS version 17.0 for frequencies of age group, gender, and IgM positive Chikungunya virus infection.Results: Out of 4329 venous blood samples collected from suspected patients of Chikungunya virus infection. 1181(27%) showed the presence of IgM of Chikungunya virus (CHKV) infection. Majority of the patients were in the third decade of their lives with median age of 38.74 years. The proportion of males was slightly more 605 (51%) than females 575 (48%) (Table I). Age group 16-44 years showed high prevalence 627 (53%) as compared to other age groups (2017-2018) (Figure: 1). Incidence of CHIKV was higher in October and November 2017(37.8%), than 2018 (Figure: 2).Conclusion: This study concluded that the frequency of Chikungunya virus Infectionwas higher during the ststperiod from 1October till 31November 2017
Dr. Fouzia Zeeshan Khan, Fatima Fasih, Mohammad Sohaib Tauheed, Saba Hassan, Sambreen Zameer. (2021) Frequency of Chikungunya Virus Infection in the Tertiary Care Hospital of Karachi, Journal of Islamic International Medical College, Volume 16, issue 3.
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