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OBJECTIVE: To determine the demographic, clinical and radiographic features
of the central giant cell granulomas (CGCG) of jaws.
METHODS: This observational study was conducted at Outpatient
Department of Oral and Dental Hospital, Khyber College of Dentistry
Peshawar and private clinics at Peshawar, Nowshera, Mardan and Kohat, from
June 2006 to May 2018. Sixty-eight cases of CGCG of jaws, excluding known
patients of syndromes and hyperparathyroidism, confirmed by biopsy were
included in this study by convenience sampling.
RESULTS: Age ranged from 4-50 years with mean of 22.35±11.68 years. Most
of the patients were from 21-30 years (n=28/68; 41%). CGCG were slightly
more frequent in females (n=36/68; 53%) as compared to males (n=32/68;
47%). Anterior part of mandible was the most common site involved (n=32/68;
47.1%). There was cortical expansion in 53 out of 68 cases. Tooth mobility was
found in more than half of cases (n=36.68; 52.9%). Only four cases of lip
numbness, while no case of spontaneous bleeding (three cases of bleeding on
touch were seen). Among all the radiolucencies, majority of CGCG (n= 40/68;
58.8%) had well define borders while 41.2% of CGCG had diffuse borders.
Majority of CGCG were unilocular. Tooth resorption was seen in about onethird patients (n=24/68; 35.3%).
CONCLUSION: The clinical and radiographic features of some CGCG show
benign features like non-mobile teeth, only buccal cortical expansion, uniloculor
radiolucency, no tooth resorption and well define borders. However, some
show aggressive features like tooth mobility, bicortical expansion, multiloculor
radiolucency, root resorption and ill-defined borders.
Umar Nasir, Bibi Maryam, Tehmina Marwat, Neelofar Nausheen. (2019) CLINICAL AND RADIOGRAPHIC PRESENTATION OF CENTRAL GIANT CELL GRANULOMAS OF JAWS, KHYBER MEDICAL UNIVERSITY JOURNAL, Volume 11, Issue 4.
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