Abstract
As an alternative of antibiotic growth promoters, medicinal plants are the most popular
options. Papaya leaves are good source of vitamins, minerals, antioxidants and enzymes which provide
aid in digestion of carbohydrates, proteins and fats and overcome the microbial load and used as a growth
promoter and antibiotic in broiler performance. This study was carried out in order to evaluate the effect of
papaya leaf extract in drinking water as a replacement of commercial antibiotic on blood hematology, serum
biochemistry and immune response of broilers for the duration of 35 days.
Methods: In this experiment, 180 one-day old chicks were randomly distributed into 6 treatments. Each treatment
was divided into 3 replicates having 10 chicks each. Feed was offered ad-libitum to broilers. Six treatments; G1
{(basal diet + antibiotic growth promoter (enramycin) + coccidiostat (salinomycin)}, G2 (basal diet without
antibiotic growth promotor and coccidiostat), G3 (basal diet + 0.5% papaya extract), G4 (basal diet + 1.0%
papaya extract), G5 (basal diet + 1.5% papaya extract) and G6 (basal diet + 2.0% papaya extract) were
designed. Blood samples were taken for serum biochemistry, hematology and titer against Newcastle disease.
Data were analyzed using analysis of variance technique by completely randomized design using SAS and
Tukey’s test were used for comparison of means.
Results: Birds received various level of papaya extract had no effect on serum biochemistry and hematology
parameters except triglyceride levels which were significantly lower in G2 (15.00±15.00, commercial diet) and
G6 (17.43±9.87, commercial diet + 2% papaya extract) at 17th day and 35th day where it failed to show significant
difference. However, Newcastle disease and infectious bursal disease titers were not affected by the treatments.
Muhammad Khalid Bashir, Muhammad Ashraf, Shahid Ur-Rehman, Sadia Razzaq, Muhammad Qamar Bilal, Sayeda Mariam, Madiha Tabbasum. (2019) Effects of Carica Papaya Leaf Extract on Blood Hematology, Serum Biochemistry and Immune Response of Broilers, Advancements in Life Sciences, Volume 7, Issue 4.
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