Abstract
Objective: The present study is aimed to determine the anti-nociceptive activity of crude methanol extract of Hypericum
oblongifolium.
Material and Methods: In vivo acetic acid induced writhing test was used for anti-nociceptive effects in mice at 10, 20 and 30
mg/ kg body weight respectively intraperitoneally.
Results: The extract doses of 10, 20 and 30 mg/kg revealed significant inhibitory effect (P < 0.001) in acetic acid induced
writhing test.
Conclusions: The methanol extract of medicinal plant Hypericum oblongifolium showed significant analgesic / anti-nociceptive effects in animal models and thus supports the traditional uses of the plant in painful conditions.
Jamshed Ali, Faryal Ali, Arsalan Khan, Muhammad Junaid. (2020) PHARMACOLOGICAL SCREENING OF HYPERICUM OBLONGIFOLIUM FOR ITS ANALGESIC EFFECT IN MICE, Journal of Medical Sciences, Volume 28, Issue 3.
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