Abstract
Objective: To find the association between zinc deficiency and febrile seizures in children of 6 months and 5 years
of age.
Materials and Methods: Cross-Sectional Descriptive Study was carried out at the Department of Pediatrics,
Benazir Bhutto Hospital, Rawalpindi for six months (From 11th March to 31st August 2017). After taking approval
of the Ethical Research Committee of Rawalpindi Medical College and taking informed consent from the parents/
guardians, children selected according to the inclusion/exclusion criteria.
Patient profile including name, age, sex, address, hospital number, serial number, date of inclusion in the study
was noted. Data was collected from the Patient’s charts and/or by direct interview of the child’s guardian.
Using aseptic measures, 2ml of blood from venipuncture utilizing a 22-gauge antiseptic needle, in no more than
24 hours of hospital visitation was reserved. Evaluation of serum zinc was completed in no more than 6 hours of
collection. The copy was then given to the lab testing and thus this report was then approved by the physician.
Results: In our study, out of 145 cases, 52.41% (n=76) were between 1-3 years of age whereas 47.59% (n=69) were
between 4-6 years of age, the mean and standard deviation was calculated as 3.54 + 1.50 years, 50.34% (n=73)
were male whereas 49.66% (n=72) were females. Mean serum zinc levels were calculated as 64.28 + 12.13 mcg/dl.
The frequency of hypozincemia in febrile seizures among children presenting at tertiary care hospitals was 54.48%
(n=79).
Conclusion: These analysis outcomes depicted that children with febrile seizures had notably lesser serum zinc
measures
Syeda Mamoona Qudrat, Najaf Masood, Ammara Khalid, Tanzeela Rani, Mobeen Tabussum, Rai Mohammad Asghar. (2020) Children with Febrile Seizures have Lower Zinc Levels, The Journal of Rawalpindi Medical College, Volume 24, Issue 3.
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