Abstract
Objective: To compare the efficacy of nifedipine and salbutamol in the treatment of preterm labour.
Methodology: This comparative clinical trial was conducted in the department of Obstetrics and Gynaecology Hayatabad Medical Complex Peshawar
on 176 pre natal patients. All patients with preterm labour aged 15-45 years
with any gravida or parity presenting through outpatient department (OPD)
or emergency room (ER) with uterine contraction associated with cervical effacement and dilatation before 36 weeks and 6 days of gestational period
were included in the study. Patients were divided into two groups by lottery
method. Women in group A were put on tablet nifedipine while women in
group B were given salbutamol. The drug was considered effective in case of
cessation of the uterine contraction within 2 hours of initiation of the drug
and continuation of the effect till minimum of 48 hours.
Results: Mean age was 28.53 ± 5.84 in group A and 28.26 ± 5.47 in group
B. Nifedipine was found to be more effective than salbutamol in prolonging
pregnancy for more than 48 hours, whereas no significance difference was
found between the two drugs in delaying delivery after 1 week of pregnancy
prolongation (30.68% versus 32.95%).
Conclusion: Nifedipine is more effective than salbutamol in the treatment of
preterm labour.
Saima Ayub, Nudrat Ayub, Noreen Ayub, Rukhsana Karim, Shamshad Begum. (2020) COMPARISON OF EFFICACY OF NIFEDIPINE AND SALBUTAMOL IN THE TREATMENT OF PRETERM LABOUR, Journal of Postgraduate Medical Institute, Volume 4, Issue 2.
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