Abstract
Objective: To analyze the utility of model of end stage liver disease sodium scores in predicting mortality following acute variceal
bleeding in patients with Cirrhosis due to hepatitis C.
Study Design: Descriptive case series
Place and Duration: Department of Gastroenterology and Hepatology, Pakistan Institute of Medical Sciences (PIMS), Islamabad from
January 4, 2011 to January 4, 2012.
Methodology: 240 patients with HCV Cirrhosis presenting with history of haematemesis or melaena due to varices diagnosed on
Esophagogastroduodenoscopy (EGD) were enrolled in study. On the first visit, blood samples were sent to hospital lab for serum
Bilirubin, Sodium, Creatinine and INR. All these results are verified by pathologist. These patients were scored according to Model
for end stage liver disease Sodium (MELD-Na) scoring systems. These cirrhotic patients were followed up for 3 months for rebleeding
and mortality by telephonic contacts to patients.
Results: Out of 80 patients with MELD-Na score <20, 21.25% patients had re-bleed, 8.75% patient died and 70% patients had no
rebreeding or death. In 80 patients with MELD-Na score 21-30, 30% patients re-bled again from esophageal varices, 21.25% patients
suffered mortality and 48.75 patients had uneventful recovery. In 80 patients with MELD-Na score 31-40 30% patients re-bled,
38.75% patients died and 31.25% patients recovered smoothly.
Conclusion: MELD-Na is reliable predictor of mortality and rebleeding in cirrhotic patients presenting with acute variceal bleeding.
Jahanzeb Maqsood, Muhammad Abdul Quddus, Syed Saif Ur Rehman, Muhammad Wajad Munir, Abida Mateen Ansari. (2020) Utility of model of end stage liver disease Sodium score in predicting mortality following acute variceal bleeding in patients with Cirrhosis due to Hepatitis C, Isra Medical Journal, Volume 12, Issue 1.
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