Objective: To determine the frequency of
Helicobacter pylori antigen in stool of patients with
chronic urticaria who presented at our tertiary care
hospital.
Methodology: This descriptive cross-section
study was carried out at department of
dermatology in collaboration with department of
pediatrics, Al-Tibri Medical College & Hospital and
Isra University Karachi Campus, during a period of
one year. Patients with chronic urticaria of both
genders and all ages were selected by nonprobability convenience sampling. Patients with
known co-morbidities and other causes of urticaria
as well as those with acute urticaria were
excluded.
Results: Out of 116 patients, 73 had positive H.
pylori antigen in their stool. Females patients
(67.2%, n=43) and those who had angioedema
(66.7%, n=16) were more likely to have H. pylori
antigen positive. Serum level of immunoglobulin E
was found quite elevated in patients who were
positive for H. pylori antigen
Conclusion: Considerable number of patients
with chronic urticaria had H. pylori antigen in their
stool. This antigen is internationally recognized to
be the cause of chronic urticaria in many countries.
(Rawal Med J 202;45:523-526).
Humaira Maryum Agha, Krishan Lal, Sadaf Ahmed Asim, Yasmin Channa, Farah Saleem. (2020) Frequency of Helicobacter pylori antigen in stool of patients with chronic urticaria, , Volume 45, Issue 3.