Abstract
Objective: To estimate the frequency of metabolic
syndrome (MetS) among apparently healthy pre
and post-menopausal women and association of
hematological parameters with the risk factors of
MetS like cardiovascular disease (CVD) and
diabetes mellitus type 2 in pre and postmenopausal women.
Methodology: This comparative cross-sectional
study was conducted in Department of Physiology,
University of Sindh with collaboration of LUH
(Liaquat University Hospital and Diagnostic &
Research, (DR) Laboratory LUMHS on 137
participants purposively selected who underwent
a general health examination attending LUH OPD
& private clinic, without MetS knowledge.
Females between 25 to 65 years of age, who were
not taking any medication, with previous history of
regular menstrual cycle (premenopausal women)
& who underwent natural menopause (postmenopausal women) were included in the study.
Results: We found 59.9% prevalence of MetS,
higher in post-menopausal compared to premenopausal subjects. The distribution of
individual risk components of MetS were
statistically highly significant in post-menopausal
subjects (p<0.05). Systolic BP ≥130 mmHg was
the least documented risk element in premenopausal subjects; while triglyceride levels
≥150 mg/dl was the least risk element for MetS in
post-menopausal women.
Conclusion: Hematological parameters (RBC,
WBC, Hb levels) can be used for the early
detection of MetS in individuals with high risk,
along with, individual risk components these can
be used for better diagnosis of non-communicable
diseases such as CVD and T2DM. (Rawal Med J
202;45:541-544).
