Abstract
Objectives: To see the prevalence and outcome of Human brucellosis in
Makkah. Study Design: Cross Sectional study. Setting: Security Forces Hospital, Makkah.
Period: August 2016 to August 2019. Material & Methods: Patient’s data was collected
for the last 3 years. Simple randomized sampling technique was adopted and data was
collected and analyzed using SPSS version 24. Univariate comparisons were done by using
Chi square test. Results: This study enrolled 241 patients with predominant age group of 15-
40 years (41.9%). Incidence rate in Makkah is 4.01 per 100,000 persons per year. Male were
predominant (67.2%). About fifty-seven (57.3) % patients belonged to urban areas and the risk
of acquisition of brucellosis was the consumption of unpasteurized milk in 138 (57.3%) patients.
Most common clinical presentation was fever (95.4%) without a definite focus in 200 patients
(83%), Eighty-three (83%) patients had uncomplicated brucellosis. The most common (67.2%)
treatment regimen was rifampicin and doxycycline for 6 weeks. Relapse rate was reported
10.8%. Death rate was reported to be 0.9%. Conclusion: Brucellosis still affects health of Saudi
population and causes economic burden. It is recommended to keep up the efforts to decrease
the brucellosis incidence rate toward zero.
