Abstract
Objectives: To compare mean length of hospital stay (LOHS) after treatment
with nebulized hypertonic saline (HS) versus normal saline (NS) in hospitalized children with
acute bronchiolitis (AB). Study Design: Randomized Control Trial. Setting: Department of
Pediatric Medicine, The Children’s Hospital and Institute of the Child Health, Multan. Period:
July 2018 to January 2019. Material & Methods: A total of 206 hospitalized children having
AB were enrolled. Group A (n=103) was nebulized with 2 ml of 3 % HS while group B (n=103)
was nebulized with 2 ml of 0.9% saline solution. Clinical severity score was calculated daily to
monitor progress of patients. Patients were discharged from hospital with clinical severity score
of 4 or less and length of hospital stay was noted. Results: Overall, mean age was 5.83±4.48
months. Among 206 patients 139 (67.5%) were males and 67 (32.5%) females. Mean duration
of disease was noted to be 3.57+2.2 days. In Group-A, mean LOHS was 36.29+18.4 hours in
comparison to 39.15+16.1 hours in Group B (p-value = 0.2365). Conclusion: Nebulized HS
3% and NS 0.9% were not found to have any significant advantage over each other in terms of
LOHS among hospitalized children having acute bronchiolitis.
Maleeha Saleem, Maria Saleem, Asim Khurshid. (2020) Hypertonic saline versus normal saline nebulization in hospitalized children with acute bronchiolitis., The Professional Medical Journal, Volume 27, Issue 12.
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