Abstract
Autoimmune hemolytic anemia (AIHA) is described by destruction of Red Blood Cells (RBCs) as a result of
binding of antibodies to red blood cell surface antigens. White blood cells are usually normal and
hyperleukocytosis is rare. The most common microorganism that has been associated with these hemolytic
processes is Mycoplasma pneumoniae. We presented a case study, a 4-year-old boy child who was
diagnosed AIHA by warm antibody testing with high leukocyte count. The patient was treated with
methylprednisolone, intravenous immunoglobulin and clarithromycin. During treatment, the leukocytosis
became normal. The clinical condition and vital signs improved. The purpose of this study was to highlight
hyperleukocytosis in AIHA caused by Mycoplasma pneumoniae.
Ilknur Uzunoglu, Nursima Cukadar, Egemen Tavrak, Sema Yilmaz, Elif Suleymanoglu. (2020) Hyperleukocytosis: A Rare Manifestation of Autoimmune Hemolytic Anemia , The Pakistan Journal of Medicine and Dentistry, Volume 9, Issue 4.
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