Abstract
Plant-pathogenic fungi and public human health are subject of utmost importance to the researchers; therefore, it is necessary
to find alternative potent antimicrobial agent. Effectiveness of seven extracts from Euryops arabicus plants were tested against
twelve of plant and human pathogens using well diffusion methods. Herbal plants are the main sources of many useful
chemicals compounds, therefore, chemicals profiling by GC-MS and heavy metals were estimated for avoiding the risk of
health hazards. Plants pathogens include Alternaria alternata, Drechslera halodes, Fusarium oxysporum F. sp. lycopersici,
Penicillium expansum, Pythium ultimum and Rhizoctonia solani and human pathogens include Staphylococcus aureus, Shigella
flexneri, Micrococcus luteus, Pseudomonas aeruginosa, Klebsiella oxytoca, Proteus mirabilis and Candida albicans were
inhibited to various degrees by chemicals extract from Euryops arabicus plants. Aqueous extraction by cold water did not
show any activity against all tested microbes while hot water extract had an activity only against human pathogens. In all cases
the effectiveness of Euryops arabicus extract against human pathogens more potent than plant pathogens also fresh extraction
had an activity more than dry extractions. Chloroform and diethyl ether extracts had the highest activities against Klebsiella
oxytoca and Candida albicans while Staphylococcus aureus is the least pathogenic bacterial strains inhibited by Euryops
arabicus solvent extracts. Diethyl ether extracts had the maximum affect on the growth of all tested plant pathogens, while
acetone extract had the minimum affect. Methanol and chloroform extracts exhibited almost the same trends of inhibition
activities against Drechslera halodes and Pythium ultimum. GC-MS showed that Euryops arabicus leaves contains chemicals
exhibit important biological activities as antimicrobials and antifungal. Trace amount of heavy metal was found in E. arabicus
leaves. Therefore, E. arabicus leaves could be used as an important source to get natural antimicrobial agents for both plant
and human pathogens
