Abstract
Objective: To identify the cervical vertebral anomalies in patients with cleft lip and palate, and to compare
unilateral and bilateral cleft lip and palate.
Methods: The retrospective cohort study was conducted in 2018 at Department of Orthodontics, Ege University,
Izmir, Turkey, and comprised non-deteriorated lateral cephalometric radiographs of non-syndromic patients which
showed the entire cervical spine. The radiographs were divided into two groups, with group A having those of
patients with cleft lip and palate exposure, and control group B having those with non-exposure. Within group A,
unilateral and bilateral cleft lip and palate cases were compared. Data was analysed using SPSS 22.
Results: Of the 220 subjects, 110(50%) were in group A with a mean age of 15±6.3 years, and 110(50%) were in
group B with a mean age of 15±2.1 years. Within group A, 56(50.9%) subjects had unilateral and 54(49.1%) had
bilateral cleft lip and palate. Cervical vertebral anomalies were found in 71(64.5%) patients and 45(40.9%) controls
(p<0.001). Among those with bilateral condition, it was found in 41(75.9%) and in unilateral 56(56.6%) (p<0.05).
Occipitalisation was 21(38.9%) in bilateral and 4(7.1%) in unilateral cases (p<0.001). Fusion was higher in bilateral
patients 16(63%) compared to 23(41.1%) unilateral (p<0.05). Posterior arch deficiencies were found in 30(27.3%)
patients in group A and 18(16.4%) controls in group B (p<0.05). Fusion was seen in 57(51.8%) group A patients and
33(30%) group B controls (p<0.001).
Conclusion: Cervical vertebral anomalies were mostly found in patients with cleft lip and palate. In patients with
bilateral condition, more than one anomaly was seen.
Ege Dogan, Gulen Ozses Ergican, Servet Dogan. (2021) Evaluation of the cervical vertebral anomalies in patients with cleft lip and palate in Aegean region of Turkey , Journal of the Pakistan Medical Association, Volume 71, Issue 1.
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