Abstract
The objective of this study was to determine the
diagnostic accuracy of B-scan in predicting
retinoblastoma (Rb) taking Magnetic Resonance Imaging
(MRI) as a gold standard. A cross-sectional validation
study was conducted in the Radiology Department of
Fauji Foundation Hospital from May 20 to Nov 20, 2017.
Children fulfilling the inclusion criteria were selected after
informed consent and detailed history was taken for
investigation of Rb. B-scan of both eyes was done using
7.5-10 MHz probe, followed by MRI of both eyes in the
same patients using 1.5 Tesla MRI machine with the help
of qualified MRI technicians. Data analysis was done by
SPSS version 16.0. The diagnostic accuracy, sensitivity,
specificity, PPV and NPV of B-scan in prediction of Rb as
compared to MRI was 90.45%, 82.28%, 90.54% and
90.28% respectively. The study concluded that diagnostic
accuracy of B-scan as compared to MRI is substantial in
Retinoblastoma.
Sana Murad, Ishtiaq Ahmed, Hania Ali, Maria Ghani, Saba Murad. (2021) Diagnostic accuracy of B-scan in predicting retinoblastoma in children, taking Magnetic Resonance Imaging of orbits as gold standard, Journal of the Pakistan Medical Association, Volume 71, Issue 1.
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