A study was carried out to document the use of urea and copper sulphate in different combinations in broilers as both the
compounds are invariably present/used in poultry feed in Pakistan. The total erythrocyte count (TEC), packed cell volume
(PCV) and haemoglobin (Hb) showed a decrease, while lymphocytes increase in birds fed higher levels of urea and copper
after the second week. The monocytes increased in birds fed lower levels of urea and copper alone after withdrawal period.
The serum total proteins and globulins decreased (P<0.05) in birds fed lower levels of copper alone and when higher levels
of both the compounds were used together and these remained lower after the end of the withdrawal period. While albumin
decreased in birds fed higher levels of both the compounds after the second week of treatment but returned to non-significant
levels during the withdrawal period. The fibrinogen concentration increased in birds fed lower levels of urea and copper
together, while decreased in birds fed high levels of both the compounds together after the first week of treatment. At the end
of the second week, the fibrinogen decreased in birds fed lower levels of urea and copper alone and in those fed higher levels
of both the compounds together. However, at the end of withdrawal period fibrinogen showed a decrease in all treatment
groups. It was concluded that the hematological parameters especially those related to RBCs and the serum proteins were
affected by the combined use of both the compounds at higher levels (2% urea+1000 mg copper sulphate).
S. Shabbir Bhatti, M. Tariq Javed, Razia Kausar, Farah Deeba, Farah Akhtar, Akhtar Rasool. (2015) Urea And Copper Sulphate In Different Combinations Alter Haematology And Some Serum Proteins In Broilers, , Volume-52, Issue-2.