Abstract
Health outcomes of transplantation require strict medication compliance.
Non-compliance with immunosuppressive medications after renal
transplantation is considered to be a major cause of graft rejection and
loss. There are diverse reasons for non-compliance, including: lack of
financial resources, lack or perceived severity of consequences, health
and religious beliefs, social support, disease characteristics, medication
adverse effects, and treatment complexity. A systematic review of the
literature on medical non-compliance after renal transplantation was
carried out to identify factors leading to non-compliant behavior among
renal transplant recipients (RTRs) to prevent graft loss. The aim was to
highlight commonalities facilitating the clinicians identify patients for
early intervention. It is found that recipients at a higher risk of noncompliance after renal transplants were younger, female, unmarried,
recipients of living donor transplants and had been transplanted for a
longer time with a history of a previous transplant. Findings also
suggested that psychosocial factors such as stress, depression, lack of
coping skills and avoidant behaviors, lack of perceived control on health
out comes, locus of control attributed to powerful others, lack of
perceived social and family support, and low self-efficacy were
significant predictors of non-compliance. Significance of compliant
behavior after renal transplantation, reasons for non-compliance and its
relationship to organ loss are discussed.
Fatima Kamran. (2015) Factors of Non-Compliance in Renal Transplant Recipients: A Systematic Review, Journal of Behavioural Sciences, Volume 25, Issue 2.
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