Abstract
BACKGROUND: Nicotine use is reported more in Schizophrenic patients as compared to general population, which results is decrease efficacy of psychotropic medicines, thus increased severity of illness. OBJECTIVE: The objective of this study is to evaluate the severity of schizophrenia following tobacco use. METHODOLOGY: This cross-sectional study was conducted at department of Psychiatry Civil Hospital Karachi, Pakistan. Patients were recruited using convenience sampling technique. Clinical symptoms in patients were measured by the 18-item Brief Psychiatric Rating Scale (BPRS), scored 1–7 on each item. RESULTS: Out of the 276 patients included in the study, more than half of the participants were tobacco addicts (n=150, 54%). The statistical analysis showed significant relation (p value=0.04) between the Brief Psychiatric Rating Scale (BPRS) and tobacco addiction. CONCLUSION: This study found that schizophrenia patients with tobacco addiction had worse psychiatric symptoms as compared to those who are not addicted to tobacco.

Washdev, Zarmeen Qamar, Priyanka, Kheenpal Das, Hina Rajani, Nauman Hashmani, Shah Kamal Hashmi, Raza ur Rehman. (2018) Evaluation of Severity of Schizophrenia in Tobacco Addicts, Journal of Liaquat University of Medical and Health Sciences, Volume-17, Issue-1.
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