Abstract
OBJECTIVE: To compare the efficacy and safety of manual vacuum aspiration, and oral misoprostol in incomplete miscarriage.
STUDY DESIGN: Comparative randomized controlled trial study.
STUDY SETTING: Department of Obstetrics & Gynaecology (Unit-II) Liaquat University Hospital
Hyderabad, Sindh from May 2011 to April 2012.
MATERIAL AND METHOD: All eligible women who full filled the inclusion criteria were included
in study after taking written informed consent. A total 222 women were included in study. In
each group 111 were randomized either with 600 microgram ST mom or suction evacuation by
MVA. Sample was randomized using computer generated random sequence. Opaque sealed
study envelop were used for allocation. Primary outcome measure was to assess the efficacy of
method in form of complete evacuation. Secondary outcome measure was occurrence of complication.
RESULTS: 111 patients were randomized in each group. Mean age (years), parity and gestational age of study population were 28.4± 5.2, 3± 2 and 8.9± 12. Three patients in misoprostol
(ST mom) group complain of pain while in MVA group none of patient complain of pain. So for
safety is concern MVA is safer than misoprostol (p-value less than 0.031).
CONCLUSION: Both MVA and misoprostol can be used, as an effective method of uterine
evacuation in incomplete abortion of < 12 weeks. MVA is significantly safer than misoprostol in
terms of side effects.
Chandra Madhu Das, Madhu Sharma, Kusum Pardeep, Farkhunda Khurshid. (2014) To Compare the Safety and Efficacy of Manual Vacuum Aspiration with Misoprostol (ST mom) 600mg in Incomplete Miscarriage, Journal of Liaquat University of Medical and Health Sciences, Volume-13, Issue-3.
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