The present study explores the levels of psychosocial stress and type | personality traits among hepatitis C
patients. A sample of 200 hepatitis C patients was taken from the Out Patient Department of
Gastroenterology Department of Pakistan Institute of Medical Sciences (PIMS) Islamabad. To assesses the
psychosocial stress and type 1 personality traits the Stress Inventory was administered on the patients Our
results indicated a positive correlation between severity of the disease and object dependence loss,
disclosure of negative experiences and egoism. Our results also showed negative correlation between
severity of disease and rationalizing conflicts / frustrations. Furthermore, a significant difference in
disclosure of negative experiences and egoism was found between patients who have received interferon
therapy and those who have not yet received interferon therapy. The findings of this study have several
implications for the Gastroenterologists and other relevant professionals in understanding the needs of
hepatitis C patients with respect to their condition before and after receiving interferon therapy.