hyperhomocysteinemia (Hcy) is an independent risk factor for cardiovascular diseases (CVD) and
associated with primary causes of mortality and morbidity throughout the world. Association between Hcy
and CVD has been a question for biologists over the last five decades. The circulating levels of Hcy can
be increased by defects in enzymes involved in the metabolism of several B and therefore for homocysteine.
Although researchers have yielded conflicting findings on the link between homocysteine and CVD risk, but there
is convincing evidence on link between B vitamin deficiencies and increased CVD risk. This review identifies the
research conducted on this subject matter and provides a framework for the factors associated with Hcy and
CVD.
