Abstract
With the expansion and development of industrial technology, frequent application of various synthetic
chemicals like pesticides, insecticides and arsenic has lead to contamination of both aquatic and trestrial
ecosystem acros the globe. Among different synthetic chemicals arsenic poisoning has become a huge threat
to ground water in many parts of the world. Therefore, this study was planned to examine the adverse effects
of sodium arsenite on the morphology (gross and microscopic structure) of testis in rabbits. A total of 20
adult male rabbits were procured and randomly divided into two groups. Group (A) served as control and
rabbits in group (B) were exposed to sodium arsenite orally (@ dose of 10mg/kg/day for a period 60 days.
Results indicated significant (p<0.05) lower values of testicular weight, scrotal length and width, testicular
volume, volume occupied by 10 seminiferous tubules and volume of the individual leydig cells in treated
rabbits. The exposure induced degenerative changes in testis including wavy contour of seminiferous
tubules, vacuolization in the germinal epithelium and germ cell loss was recorded in the treated group. In
conclusion, it was observed that arsenic may induce male reproductive effects by negatively affecting the
testicular volume, leydig cell population and volume of the leydig cells.
Riaz Hussain Pasha, Anas Sarwar Qureshi, Adnan Ali, Saif-Ur-Rehman, Muhammad Akram Khan. (2021) Exposure to Arsenic Induces Histomorphological Alterations in Testis of Rabbits, Asian Journal of Agriculture and Biology, Volume-09, Issue-2.
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