Abstract
Chenopodium quinoa is a newly introduced drought resistant crop in Pakistan. Studies
regarding the efficacy of bioactive compounds present in this plant are scarce. Therefore, the current
investigation was carried out to identify the antimicrobial, antioxidant and anticancer compounds present
in ethyl acetate fraction of methanolic extract of inflorescence of C. quinoa.
Methods: Dry powdered inflorescence of the test plant was macerated with methanol and partitioned through
different organic solvents on the basis of increase in polarities beginning with n-hexane followed by chloroform
and ethyl acetate. GC-MS analysis was performed for the identification of bioactive constituents present in ethyl
acetate fraction.
Results: The GC-MS analysis revealed the presence of 15 different phytochemicals. Among these, 1,2-
benzedicarboxylic acid, diisooctyl ester (15); 9,12-octadecadienoic_acid-(Z,Z) (13); 8,11-octadecadienoic_acid,
methyl ester (12); hexacosanoic acid, methyl-ester (11); hexadecenoic acid,2-hydroxy-1-(hydroxymethyl) ethyl
ester (14); n-hexadecanoic acid (10); hexadecenoic-acid, methyl ester (8); 2-propenoic acid,3-[4-(acetyloxy)-3-
methoxyphenyl]-, methyl ester (7); 1,6,10,14,18,22-tetracosahexaen-3-ol,2,6,10,15,19,23-hexamethyl-,(all-E)-
(9) and undecane (1) were present in moderate to abundant concentrations. Biological activities of the identified
compounds were searched in the previous literature.
Conclusion: The present study concluded that ethyl acetate fraction of methanolic extract of the inflorescence of
C. quinoa contains a diverse range of potent bioactive constituents with antimicrobial, antifungal, antibacterial,
cancer preventive, anti-inflammatory and cytotoxic properties.
Iqra Haider Khan, Arshad Javaid. (2020-2021) Anticancer, antimicrobial and antioxidant compounds of quinoa inflorescence, Advancements in Life Sciences, Volume-8, Issue-1.
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