Abstract
Background: Hypothyroidism is a rare finding in children having celiac disease but it has severe effects on
mental & physical health of children.
Objective: To assess the frequency of hypothyroidism in children diagnosed with celiac disease.
Methods: This cross sectional study was conducted at Department of Pediatrics, Military Hospital and Dr. Akbar
Niazi Teaching hospital, Bhara Kahu. 60 consecutive children having celiac disease (positive anti-TTG and
endoscopy) were included in the study. Thyroid function tests were done to assess thyroid function. TSH
≥5mIU/L with T4<7.5µg/L as hypothyroidism. Data was a recorded on proforma and analyzed through SPSS v.
21.0.
Results: The mean age of children was 6.57±2.18years. There were 20 (33.3%) males and 40 (66.7%) females. Out
of 60, hypothyroidism was detected in 2 (3.3%) cases.
Conclusion: Hypothyroidism is present in only very few children with celiac diseases. But children with celiac
disease should be screened for hypothyroidism, as they may be asymptomatic and can have hazardous
consequences.
Qurat Ul Ain Khalid, Shamama Hassan, Wajeeha Amber, Imran Mahmood Khan, Munir Akmal Lodhi. (2019) Frequency of Hypothyroidism in Children of Celiac Disease, International Journal of Pathology, Volume.17, Issue-4.
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