Primary hyperparathyroidism is a common cause of hypercalcemia in outpatient practice. The incidence of primary hyperparathyroidism is increasing with age and more common in women than in men. 80-85% of cases of primary hyperparathyroidism are related to single parathyroid adenoma. The majority of parathyroid adenomas contain a mixed cell population with predominant of chief cells. Primary hyperparathyroidism with clear cell adenoma is very rare. There are a few reported cases in the literature with deferent presentation. Skeletal complications of primary hyperparathyroidism are less nowadays and the incidence of renal stones has fallen. Here we report a case of water clear cell adenoma associated with primary hyperparathyroidism presented with severe skeletal and renal manifestation.
Abdel Rahman M. Radaideh. (2017) Large water cell parathyroid adenoma associated with primary hyperparathyroidism presented as femur fracture with recurrent renal stone formation, , Volume-42, Issue-3.
