Abstract
The present study deals with the analysis of serum total proteins and fractions (albumin, total globulins, gamma globulins and non-gamma globulins) of active and passive smokers. Blood samples of 180 cigarette smokers were collected from different locations of Lahore and 60 healthy non-smokers from University of the Punjab, Quaid-e-Azam campus Lahore, in terms of comparable age, height, weight and socioeconomic set up. Serum protein profile was analyzed using commercially available kits by using automated clinical chemistry analyzer. Serum total proteins have shown a significant decrease in smokers in comparison with controls. A significant depression in serum albumin was observed in smokers due to increased excretion of albumin in bound state with the chemicals, whereas, total globulins, gamma globulins and non-gamma globulin serum proteins have shown significant increase in smokers. Our findings provide primary information about fractions and total serum proteins of cigarette smokers. The decrease in albumin justifies the reduction in total serum proteins and elevation in globulins. Smoking cessation plays a significant role in recovery of these proteins.
Nabila Roohi, Mehjabeen, Samina Ashra. (2017) Effects of cigarette smoking on serum proteins profile in male active and passive smokers, Punjab University Journal of Zoology, Volume 32, Issue 2.
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