Abstract
Depression is a common psychiatric disorder which is characterized by moodswings, aversion from activity and apathy which affects the thoughts, behavior and feelings of wellbeing. Honey and curcumin, traditional folk medicines, are thought to steadfast the defense
mechanisms of body against oxidative stress which is a key factor in elevating depression. This study is designed to reveal the efficacy of honey and curcumin against depression in rat model. 24 male wister rats were randomly divided into 4 groups. After the trial, blood biochemistry
was done in which antioxidant enzymes like SOD, Catalyze, Glutathione peroxidase were performed that shows significantly high levels in the blood than the group that was treated with nicotine and shows a positive correlation with the days at which the rat’s groups were given a supplemented feed. Total antioxidant capacity and antioxidative stress shows significant results by the selected treatment.
Muhammad Rizwan Tariq, Muhammad Naveed Sheas, Abid Muhammad, Khubaib Ali, Haris Rasool, Muhammad Nouman Rafique. (2019) Exploring the Potential of Honey and Curcumin as Antidepressent, Punjab University Journal of Zoology, Volume 34, Issue 1.
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