• Iqra Ayub

• Zunera Tanveer

• Mohammad Zahid Mustafa

• Roha Talat

• Tauseef Muhammad Asmat

• Irshad Ahmad

• Hafiz Muhammad Ali

• Zia U Din

• Asadullah

Abstract

There are different proteins with different concentrations present in human serum, post-translational modifications or aberrant expression of these proteins is reported as signs which indicate the process of carcinogenesis in human body. The aim of the present study was to profile the differentially expressed serologic proteins using Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis. In this study fifty serum samples of gastric cancer (GC) patients and ten healthy donors were screened by SDS-PAGE to estimate the expression of proteins and to compare these proteins with the healthy donors used as control. The results showed that three different proteins were differentially expressed in GC patients while comparing with healthy donors used as control which can be further used as potential biomarkers to diagnose gastric cancer in its early stages.

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